{"product_id":"endur-acin-er-niacin-500-mg-100-tablets","title":"ENDUR-ACIN ER NIACIN 500 mg 100 Tablets","description":"\u003ch2\u003eENDUR-ACIN Extended Release Niacin 500mg — Clinical-Dose True Niacin for Cholesterol and Cardiovascular Support\u003c\/h2\u003e\u003cp\u003eENDUR-ACIN ER 500mg is the standard clinical-dose format of Endurance Products' flagship wax-matrix niacin — delivering 500mg of nicotinic acid per tablet in the proprietary SmartMatrix™ vegetable wax matrix with 4–8 hour controlled release. This is the dose and format most widely recommended by cardiologists and lipid specialists who use ENDUR-ACIN as their preferred niacin supplement, providing a meaningful therapeutic dose of true nicotinic acid with substantially improved tolerability compared to immediate-release niacin at the same dose.\u003c\/p\u003e\u003cp\u003eAt 500mg, ENDUR-ACIN ER delivers a clinically meaningful dose of nicotinic acid for supporting healthy cholesterol levels, endothelial function, and vascular health. Niacin's mechanism for lipid support involves inhibition of hepatic diacylglycerol acyltransferase-2 (DGAT2) — reducing VLDL triglyceride assembly in the liver — alongside reduction of free fatty acid mobilization from adipose tissue that feeds hepatic VLDL production. The result is reduced VLDL and LDL particle number (particularly small dense LDL) and increased HDL — a lipid profile shift that standard cholesterol metrics may not fully capture but that cardiovascular risk research consistently validates. The 100-tablet format provides a 100-day supply at 1 tablet daily.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNicotinic acid 500mg per tablet\u003c\/strong\u003e — clinical-dose true niacin\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSmartMatrix™ wax matrix\u003c\/strong\u003e — 4–8 hour release, reduced flushing, clinically studied\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eSupports LDL particle reduction, VLDL management, and HDL support\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e100 tablets; vegan, gluten-free\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eTake 1 tablet daily with food. Do not exceed 1 tablet daily without physician guidance.\u003c\/p\u003e","brand":"Endurance Products Company","offers":[{"title":"Default Title","offer_id":51252295303470,"sku":"000000000300090668","price":24.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0901\/3297\/1822\/files\/515x515-0007840-endur-acin-er-niacin-500-mg-100-tablets.png?v=1779658594","url":"https:\/\/www.drmattgianforte.com\/products\/endur-acin-er-niacin-500-mg-100-tablets","provider":"Dr Matt Gianforte","version":"1.0","type":"link"}