{"product_id":"grape-seed-sap-60-capsules","title":"Grape Seed SAP 60 Capsules","description":"\u003ch2\u003eGrape Seed Extract Supplement — 95% OPC Proanthocyanidins for Antioxidant and Cardiovascular Support\u003c\/h2\u003e\u003cp\u003eNFH Grape Seed SAP delivers grape seed extract (Vitis vinifera) standardized to 95% oligomeric proanthocyanidins (OPCs) — the most concentrated and pharmacologically active form of this botanical available. OPCs are a class of condensed tannin bioflavonoids composed of catechin and epicatechin monomers linked in chains (oligomers and polymers), with antioxidant capacity estimated in certain assays to exceed vitamin C by 20-fold and vitamin E by 50-fold. Crucially, OPCs are among the rare antioxidants that are both water-soluble and lipid-soluble, allowing them to protect cellular components in both the aqueous cytoplasm and the lipid-rich cell membrane simultaneously.\u003c\/p\u003e\u003cp\u003eResearch on grape seed OPCs has documented several specific mechanisms of cardiovascular benefit: they support endothelial nitric oxide synthase (eNOS) activity for healthy vasodilation and blood pressure regulation; they inhibit LDL oxidation, which is the initiating step in atherosclerotic plaque formation; they support capillary integrity through collagen cross-linking stabilization; and they inhibit platelet aggregation for healthy blood flow. In connective tissue, OPCs bind to and stabilize the triple helix structure of collagen fibers, protecting them from degradation by collagenase and elastase enzymes — making grape seed extract valuable for skin health, vein wall integrity, and joint connective tissue support. OPCs also regenerate vitamins C and E from their oxidized forms, acting as a recycler of other antioxidants in addition to their direct free radical scavenging activity.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eGrape seed extract standardized to 95% OPC proanthocyanidins\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBoth water and lipid-soluble antioxidant\u003c\/strong\u003e — protects all cellular compartments\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eSupports eNOS activity, LDL oxidation protection, and healthy blood pressure\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollagen cross-linking stabilization\u003c\/strong\u003e — skin, vein, and connective tissue support\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e60 vegetarian capsules; non-GMO, gluten-free\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eTake as directed by your healthcare practitioner.\u003c\/p\u003e","brand":"NFH","offers":[{"title":"Default Title","offer_id":51252283965742,"sku":"000000000300084779","price":42.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0901\/3297\/1822\/files\/515x515-Grape-Seed-SAP-60c-082025-BOT.png?v=1779658480","url":"https:\/\/www.drmattgianforte.com\/products\/grape-seed-sap-60-capsules","provider":"Dr Matt Gianforte","version":"1.0","type":"link"}