5-MTHF ES 60 Capsules

High-Dose Methylfolate Supplement for Robust Methylation and Homocysteine Support

5-MTHF ES (Extra Strength) 60 Capsules by XYMOGEN is a high-dose methylfolate supplement delivering an elevated dose of 5-methyltetrahydrofolate — the active, bioavailable form of folate. Designed for individuals who require greater methylation support than standard 1mg methylfolate products provide, this extra-strength formulation is typically used under practitioner direction.

When Standard Methylfolate Doses Aren't Enough

Some individuals — particularly those with significant MTHFR impairment, severely elevated homocysteine, or complex mood and neurological concerns — require higher methylfolate doses to achieve therapeutic effect. 5-MTHF ES provides that elevated dose in the same pre-activated form, ensuring the body has abundant bioavailable folate for methylation without the conversion bottleneck of folic acid.

Key Features of This High-Dose Methylfolate Supplement

• Extra-strength 5-MTHF — higher dose than standard methylfolate products
• Active, bioavailable folate bypassing MTHFR enzyme conversion
• 60 capsules — 30-day supply at 2 per day
• Supports robust homocysteine clearance and methylation cycle function
• Recommended for use under healthcare provider supervision

Who This Is For

This high-dose methylfolate supplement is best suited for adults with significant MTHFR variants, clinically elevated homocysteine, or mood and neurological concerns requiring above-standard methylfolate support — typically under the guidance of a functional medicine or integrative health provider.

How to Use

Take as directed by your healthcare provider. Not recommended for self-directed high-dose supplementation without professional guidance.