Berberine ES-5 60 Capsules

Dihydroberberine Supplement with 5x Greater Bioavailability for Blood Sugar and Metabolic Support

Berberine ES-5 60 Capsules by XYMOGEN is a next-generation berberine supplement featuring dihydroberberine (DHB) — a reduced form of berberine that research suggests is absorbed up to 5 times more efficiently than standard berberine HCl. This means effective AMPK activation, blood sugar regulation, and metabolic benefits at significantly lower doses — with improved GI tolerability.

Why Dihydroberberine Outperforms Standard Berberine

Standard berberine is poorly absorbed in the GI tract — much of a 500–1,000mg dose never reaches circulation. Dihydroberberine absorbs through a different intestinal transport mechanism with dramatically higher bioavailability, converting to berberine intracellularly where it activates AMPK and delivers its metabolic effects. The result is equivalent or superior metabolic benefit at 5x lower doses, with significantly less GI discomfort.

Key Features of This Dihydroberberine Supplement

• Dihydroberberine (DHB) — 5x greater bioavailability vs. standard berberine
• AMPK activation for blood sugar regulation and insulin sensitivity
• 60 capsules — 30-day supply at 2 per day
• Better GI tolerability than high-dose standard berberine
• Equivalent metabolic support at fraction of the dose

Who This Is For

This dihydroberberine supplement is ideal for adults who want the metabolic benefits of berberine with superior bioavailability — particularly those who have experienced GI discomfort with standard high-dose berberine or who want maximum metabolic effect from a lower capsule dose.

How to Use

Take as directed by your healthcare provider, typically 1–2 capsules daily with meals.