Berberine with MicroPQQ Advanced 30 Capsules

Berberine with PQQ — Dual-Mechanism Metabolic and Mitochondrial Support

Dr. Mercola Berberine with MicroPQQ Advanced delivers two clinically distinct compounds targeting metabolic health and mitochondrial function simultaneously — addressing two of the most interconnected aspects of cellular biology in a single formula. Berberine is a plant alkaloid extracted from Berberis species with the most extensive human clinical trial data of any botanical for blood sugar regulation, insulin sensitivity, and metabolic health. Its primary mechanism is AMPK (AMP-activated protein kinase) activation — the master metabolic switch that increases cellular glucose uptake, reduces glucose production in the liver, promotes fatty acid oxidation, and improves insulin sensitivity through mechanisms that parallel metformin's metabolic effects.

MicroPQQ (pyrroloquinoline quinone) is a redox-active compound with a unique property not found in any other known nutrient: the ability to trigger mitochondrial biogenesis — the creation of new mitochondria within existing cells. This is accomplished through activation of PGC-1alpha, the primary regulator of mitochondrial gene expression. Because berberine's metabolic benefits depend substantially on mitochondrial efficiency (AMPK activation ultimately drives energy into mitochondrial oxidative phosphorylation), and because mitochondrial dysfunction is a primary driver of insulin resistance, the combination of berberine and PQQ in a single formula creates a genuinely synergistic pair.

• Berberine — AMPK activator for blood sugar regulation and insulin sensitivity
• MicroPQQ — triggers mitochondrial biogenesis via PGC-1alpha activation
• Synergistic pair — metabolic and mitochondrial pathways are deeply interconnected
• 30 capsules per bottle
• Non-GMO, gluten-free, soy-free

Take as directed on label or by your healthcare provider.