Pantethine SR 300 mg 90 Tablets
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Pantethine SR 300mg — Sustained Release Active Vitamin B5 for Lipid Metabolism and Cardiovascular Support
Endurance Products Pantethine SR delivers 300mg of pantethine from Pantesin® — the clinically studied, highly bioavailable form of this active vitamin B5 metabolite — per tablet in a sustained-release carnauba wax matrix for gradual delivery over several hours. Pantethine is the biologically active form of pantothenic acid (vitamin B5) — specifically, it is the disulfide of pantetheine, which is the active carrier component of coenzyme A (CoA). Unlike pantothenic acid itself, which must be converted to CoA through a multi-step enzymatic pathway, pantethine is much more directly incorporated into CoA, making it the most pharmacologically active form of B5 for clinical applications targeting CoA-dependent metabolism.
Coenzyme A is arguably the most metabolically central cofactor in human biochemistry — it is required for the synthesis and oxidation of fatty acids, the Krebs cycle entry of acetyl groups, the synthesis of ketone bodies, the acetylation of neurotransmitters (acetylcholine), the synthesis of steroid hormones and bile acids, and Phase II liver detoxification reactions. Pantethine's most clinically documented application is lipid metabolism support: multiple clinical trials using Pantesin pantethine have demonstrated meaningful reductions in total cholesterol, LDL cholesterol, and triglycerides alongside increases in HDL cholesterol at 600–900mg daily doses (2–3 tablets). This lipid-modifying activity is attributed to pantethine's role in enhancing CoA availability for fatty acid beta-oxidation and reducing CoA-dependent lipid synthesis pathways.
- Pantethine 300mg from Pantesin® — the most bioavailable, clinically studied pantethine brand
- Carnauba wax sustained-release matrix — gradual delivery for optimal absorption
- Supports lipid metabolism, CoA synthesis, and cardiovascular health
- Phase II liver detoxification and energy metabolism cofactor
- 90 tablets; vegan, gluten-free
Take 1 tablet with morning and evening meals, or as directed by your healthcare provider.