Senolytic Px 15 Capsules

Senolytic Px — High-Dose Fisetin Formula for Senescent Cell Clearance

Restorative Formulations Senolytic Px is a precision-formulated senolytic supplement built around fisetin — the flavonoid with the most robust preclinical and emerging clinical evidence for selectively eliminating senescent cells ('zombie cells') from tissue. Each 5-capsule dose provides Smoketree extract 80% fisetin (2,155mg, yielding fisetin 1,724mg), Quercetin 180mg (from Sophora japonica), Fenugreek 180mg (as a bioavailability enhancer), and Organic Black Pepper 35mg (95% piperine) — a formula that uses fenugreek and quercetin to optimize fisetin's absorption and biological activity.

Senolytic therapy follows a clinically validated 'hit-and-run' dosing protocol: high doses are used for 3 consecutive days per month, followed by a rest period for the remainder of the month. This intermittent approach reflects the biology of senolytic action — senolytics need only be present during the window of senescent cell vulnerability, and continuous daily dosing is neither necessary nor recommended. Research on fisetin and quercetin senolytics at the Mayo Clinic and elsewhere has demonstrated their ability to reduce markers of cellular senescence, senescence-associated secretory phenotype (SASP) inflammatory signaling, and age-related physical decline in preclinical models and early human studies.

• Fisetin 1,724mg per 5-capsule dose (from Smoketree extract 80% fisetin 2,155mg)
• Quercetin 180mg — synergistic senolytic activity
• Fenugreek 180mg + Black Pepper 35mg — bioavailability optimization
• Hit-and-run protocol: 5 capsules daily for 3 consecutive days per month
• 15 capsules per bottle; non-GMO, gluten-free

Take 5 capsules daily for 3 consecutive days per month. Do not exceed 3 days per month, or as directed by your healthcare provider.